Student discovers fungus predicted by Albert Hoffman
Framing of LSD and Drug Policy
- Several commenters object to the article’s line that LSD “is used to treat” depression/PTSD/addiction, noting it’s Schedule I in the US and not widely available as an approved treatment.
- Others reply that clinical/experimental use does exist and point to published trials and religious exemptions, but emphasize it’s not mainstream medicine.
- Drug scheduling is repeatedly described as politically and racially motivated, contrasting criminalized psychedelics and cannabis with legal alcohol and tobacco.
- There’s debate over whether moral arguments against drugs are religiously rooted and whether the “War on Drugs” is really a “war on the poor.”
Hofmann’s “Problem Child” and Article Tone
- The “problem child” phrasing is partly criticized as stigmatizing, but multiple people note it’s a direct reference to Hofmann’s own book title.
- Some feel the article is overly rosy about therapeutic use and underplays that most LSD is used recreationally/self‑medicationally.
Significance of the Student’s Sequencing Work
- One thread questions how “significant” genome sequencing is if an external lab did the actual sequencing.
- Replies explain the likely student contributions: choosing the organism, isolating DNA, assembling the genome from reads, interpreting results, and securing a grant.
- Others stress that accidental discoveries are still real science: “chance favors the prepared mind.”
LSA, Morning Glory, and the Fungus
- Commenters note that LSA in morning glory seeds has been known for a long time; the key finding is identifying the endosymbiotic fungus that actually produces it.
- There is some confusion over whether the fungus makes LSD itself or just related ergot alkaloids; several say this remains unclear from the article.
Psychedelic Benefits vs. Risks
- Multiple personal accounts describe LSD or psilocybin as transformative or even life‑saving when other treatments failed, especially with integration therapy.
- Others recount long‑lasting trauma or personality disruption after psychedelics, even with “good set and setting,” and criticize evangelism that dismisses risks.
- A YouTube psychiatrist is cited warning that psychedelics can induce PTSD; commenters argue over how strongly to generalize that caution.
Broader Scientific and Ecological Context
- Some emphasize how common it is to discover new fungi and plant‑fungus symbioses, and how little of plant biodiversity has been genomically characterized.
- The thread connects habitat loss and genetic diversity collapse to the loss of potentially valuable biochemical “libraries” in nature.