When America first dropped acid

Psychedelics’ journey from mid‑20th‑century experiments and Cold War projects to today’s quasi‑mainstream use underpins a wide range of reflections on LSD, psilocybin and related drugs. Commenters contrast historic figures and programs like MK-ULTRA and early clinical work with the current boom in therapeutic research, decriminalization efforts, and easy access via grow kits and gray markets. Throughout, they weigh reports of life‑changing or spiritually framed benefits against accounts of trauma, medical risks (e.g., with microdosing), and commercialization and hype that can obscure both harms and realistic therapeutic value.

Accessing the article / paywalls

  • Several comments focus on bypassing The New Yorker paywall via archive links or browser extensions.
  • Some report earlier issues with infinite CAPTCHAs and DNS/Cloudflare problems, but note these seem mostly resolved.

Personal experiences with psychedelics

  • Multiple users describe occasional LSD and psilocybin use as helpful for sobriety, mood, or perspective, often preferring low or moderate doses.
  • Others report no deep insights beyond entertainment, or say any “revelations” are similar to what careful introspection could produce.
  • Some compare low-dose psychedelics favorably to alcohol for socializing; others emphasize that high-dose sessions can be life-altering in a way low doses are not.

Microdosing and health risks

  • One thread cites pharmacology: psilocybin, LSD, and MDMA are 5-HT2B agonists, and chronic stimulation may risk heart-valve fibrosis.
  • Linked papers and a legal/medical blog are used to argue that regular microdosing might be both clinically unproven and potentially harmful.
  • Others note the risk seems to be from long-term, frequent use rather than occasional higher doses.

Availability and cultivation of mushrooms

  • Several users report a dramatic increase in access to psilocybin in recent years (legal gray markets, storefronts in Canada, decriminalized areas in the US).
  • Detailed discussion of home-growing techniques (spores, “Uncle Ben’s tek,” grow kits, contamination issues) frames mushroom cultivation as an easy hobby.
  • Legal status varies by country; some note spores are legal where fruiting bodies are not.

History: CIA, MKULTRA, and early LSD

  • One branch argues the CIA significantly accelerated LSD’s spread via MKULTRA, funding synthesis and early experiments that involved later counterculture figures.
  • Others push back that LSD would likely have reached America through psychiatrists and intellectuals regardless, though CIA activity may have sped things up.
  • A podcast and FOIA story about MKULTRA records are referenced.

1960s counterculture and media amplification

  • A debated claim: the “peace and love” 1960s were largely media-created, brief, and not widespread; many adherents supposedly dropped out or became marginal.
  • Critics counter that the cultural output, political shifts, civil rights, and broader social changes show a real and consequential movement, even if numerically small.
  • Several note how media can both caricature and endlessly recycle short-lived subcultures, shaping collective memory.

Therapeutic potential vs harms

  • Some commenters report psychedelics easing depression, loneliness, acceptance of mortality (including in terminal illness), and inspiring meditation practice.
  • Others recount severe panic, long-lasting anxiety/PTSD-like symptoms, or intensification of depression after “bad trips,” sometimes over multiple years.
  • There is frustration that negative experiences are often dismissed with “set and setting” explanations and social pressure to treat psychedelics as uniformly positive.
  • A recurring view: benefits may justify risks mainly for treatment-resistant depression, PTSD, or cluster headaches; for most people, the risk/benefit is ambiguous.

Cultural, religious, and “enlightenment” debates

  • Some users see psychedelic states as tapping into religious/spiritual dimensions or echoing long-standing ethical messages (love, peace, ego reduction).
  • Others interpret these states as the brain overwhelmed by novel stimuli, then rationalizing them as “mystical” to protect its normal world-model.
  • There is disagreement over whether such experiences reveal deep truths or just intensify self-referential thinking.
  • Several draw parallels with meditation: similar states can sometimes be reached without drugs, though often with long practice.

“Should I try LSD?”

  • One user asks whether never trying, trying a few times, or regular use is “best.”
  • Responses emphasize:
    • Only consider it if you feel genuinely curious, not pressured.
    • Prior comfort with altered states (alcohol, cannabis) helps.
    • Start with low doses, in a safe, familiar setting, with trusted and ideally experienced companions.
    • Avoid if you have strong anxiety, possible psychosis risk, or family history of schizophrenia.
    • Acknowledge that trips can be both profound and terrifying, and last 8–12 hours with no off-switch.
  • Some frame psychedelics as powerful but overrated in terms of permanent “insight”; others value them as rare, highly novel experiences.

Discussion about the reviewed book / early psychedelic science

  • The book’s author participates in the thread, briefly describing a messy, iterative writing process with substantial cutting and heavy use of archival material and interviews.
  • They note that digitized archives and cooperative archivists made this historical work possible.
  • Questions arise about missing figures from the review (e.g., early facilitators and therapists); the author says some were cut because existing works already cover them, and highlights lesser-known contributors (such as early therapists who refined “set and setting”).
  • Canadian work, especially in one province, is acknowledged as historically important but largely covered by other historians.

Meta and moderation concerns

  • Early in the thread, one commenter urges focus on the specific article and book, not generic psychedelic talk.
  • Later, another notes the discussion quickly devolved into broad drug culture debate despite that request.